Rauwolscine is a potent stimulant and fat-burning compound found in the bark of the Yohimbe tree.   Traditionally used to treat certain erectile disorders, it’s finding its way into the pre-workout and thermogenic market for its focus-boosting and stimulatory effects.

What is Rauwolscine?

Rauwolscine is an isomer (same chemical formula, different structure) of yohimbine.  It is more commonly known as alpha-yohimbine (alpha Y) and exhibits all of the same effects as regular yohimbine but without the nasty side effects, as nearly all users report.

Alpha Y acts as an antagonist on the α-2 adrenoceptors in the body.  These receptors are responsible for holding onto those “stubborn” fat areas that won’t seem to go away no matter how hard you exercise or strict you eat.  By blocking these receptors, noradrenaline is increased and fatty acids from those trouble spots are liberated and can now be burned!

There’s a slew of other perks to Alpha Y, but we’ll save those for later on in the article…

Found in Nature

Rauwolfia Serpentina

Rauwolscine is one of the 3 isomers obtained from Rauwolfia Serpentina, shown above.

Yohimbine is a naturally occurring alkaloid compound found in the Pausinystalia yohimbe tree (Corynanthe yohimbe) and the plant Rauwolfia Serpentina.  Rauwolscine is one of the 3 isomers obtained from the bark of the yohimbe tree.  While all the isomers have the same chemical makeup, their structure (and therefore mechanisms of action) are different.

What are the rauwolscine benefits?

We’ve briefly touched on some of Alpha Y’s benefits, but now we’ll get into how it fuels your fitness goals:

  • Energy Booster

    Alpha Y primarily acts as a central nervous stimulant by increasing the amount of norepinephrine (NE) levels in the body.  This increase in NE leads to:

    • increased heart rate[4]
    • increased blood pressure[4], and
    • enhanced concentration.

    This mirrors many of the effects of caffeine[5] (another ingredient in Nitramine) and when combined the two provide a powerful kick to fuel your workouts.

  • Focus-Enhancer

    Working off the same principle mentioned above, Alpha Y increases the noradrenergic neurotransmission directly improving several cognitive processes including:

    • Attentiveness[3]
    • Memory[3]
    • Goal-directed behavior[3]

    Focus and energy are a great 1,2 punch for any supplement, but there’s still more…

  • Stress Reducer


    Image courtesy Wikimedia Commons

    When administered to a group of trained men (guys who work out regularly), there was a significant reduction in cortisol levels and anxiety.[6] Another perk was that the group experienced a boost in overall mood.

  • Enhances Blood Flow

    Alpha Y is a powerful vasodilator, meaning it expands your blood vessels.[7] This increases circulation throughout the body and particularly your muscles.  Better blood flow equates to better workout endurance and bigger pumps!

  • Targeted Fat Loss

    Rauwolscine targets the α-2 adrenoceptors in the body as we mentioned earlier.[5]  These buggers are responsible for holding on to fat in all those trouble spots on your body: hips, thighs, butt, and stomach in particular.

    By blocking these receptors, your body is free to liberate those unwanted fat stores from its cells allowing your body to burn those for energy.  This has been particularly effective when taken before exercise.[8]

All of these benefits point to Rauwolscine being an absolute no-brainer to include in your supplement arsenal.  But some are still hesitant to include it due to previous experiences with regular yohimbe extracts or products.

The great thing about Rauwolscine is that it is more-potent than traditional yohimbine (meaning you need a smaller dose to elicit the same benefits) while displaying none of the nasty side effects users previously had: jitters, anxiety, elevated cortisol.

Note that this is mainly from anecdotal accounts, but is extremely consistent when asking around. The key is likely in the dosing, which is usually recommended extremely small doses, as explained in the next section:


Clinical trials show that the recommended dosing protocol is 0.2 mg/kg of bodyweight.  This equates to about 18mg for a 200 lb male, but take serious caution with that number.  As with any stimulant, it is recommended to start with a low dose (2.5mg) and assess tolerance.  When combined with other stimulants (as is the case with Nitramine), you need even less than the 0.2 mg/kg of bodyweight to see the benefits!

What’s it doing in Nitramine?

Let’s see…

  • Energy… check!
  • Focus… check!
  • Better Pumps… check!
  • Superior Fat loss… check!

Rauwolscine not only will give us a much needed boost in energy to get the motor running, but will also help us to really focus during our workouts leading to the much sought after “tunnel-vision” we all want when working out.

The vasodilation benefits from rauwolscine with work in tandem with the other vasodilators already in the Myokem Nitramine pre workout supplement (Agmatine Sulfate and Higenamine) further enhancing blood flow to the muscles.  The end result is increased pumps and endurance from the additional nutrients that will be fed to the muscles.

Nitramine Pre Workout with Rauwolscine

Try the Nitramine Pre Workout today! This is Myokem athlete @NikkyFitness

Finally, if you’re using Nitramine before your morning cardio sessions, it will be particularly effective ridding the body of those last few pounds you can’t seem to banish.  Alpha Y will free those pesky fat deposits and you’ll be able to burn them off and attain the figure you’ve always wanted.

Wrap Up

As you can see, rauwolscine is a potent, multi-faceted,, and natural ingredient that you will regret not including in a pre workout. Thankfully, Myokem included it in Nitramine in its High Energy Blend!

This is one of the key components that separates Nitramine from every other run of the mill pre workout.  You’ll notice increased energy, focus, endurance and fat loss during your intense workouts and will be wondering why people avoiding supplements with yohimbine in the first place.

Ready to see how rauwolscine will elevate you to Adonis-status?  Grab a sample of Nitramine below and get ready to take your workouts to the next level!

Ready for the workout of your life?

Grab a sample and see the best deal on the web →

See the best deal on the web for Nitramine →